Perspective
The growing need for oligonucleotide therapeutics aimed at larger patient populations has driven the demand for high-quality nucleoside phosphoramidite which are building blocks for…
The growing need for oligonucleotide therapeutics aimed at larger patient populations has driven the demand for high-quality nucleoside phosphoramidite which are building blocks for oligonucleotide therapeutics.
The global oligonucleotide therapeutics market is projected to grow by USD 13.44 billion between 2022 and 2027, at a compound annual growth rate (CAGR) of 19.87%, according to a report by Technavio. This growth, driven by the expanding
RNA-based therapeutic modalities, has placed pressure on suppliers to provide consistent, high-purity phosphoramidites for large-scale manufacturing. The limited number of reliable suppliers further complicates this challenge, particularly as more companies scale up for clinical trials and commercial manufacturing…
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A new publication by MSD in Organic Process Research & Development details the process development and large-scale manufacturing of the key Northern Fragment of Enlicitide Decanoate.
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